\documentclass{jlreq}
\PassOptionsToPackage{deluxe}{luatexja-preset}
\PassOptionsToPackage{haranoaji}{luatexja-preset}
usepackage{luatexja-fontspec}
\usepackage{luatexja-preset}
\begin{document}

\def\sample{{あいうえお}{\gtfamily かきくけこ}{さしすせそ}}
\def\samplebf{{\bfseries あいうえお}{\gtfamily\bfseries  かきくけこ}{\bfseries さしすせそ}}

\begin{enumerate}
\item \sample
\item \samplebf
\item {\bfseries \sample}
\item \textbf{\sample}
\end{enumerate}

\end{document}
